Ancient origins of low lean mass among South Asians and implications for modern type 2 diabetes susceptibility.

Living South Asians have low lean tissue mass relative to height, which contributes to their elevated type 2 diabetes susceptibility, particularly when accompanied by obesity. While ongoing lifestyle transitions account for rising obesity, the origins of low lean mass remain unclear. We analysed proxies for lean mass and stature among South Asian skeletons spanning the last 11,000 years (n = 197) to investigate the origins of South Asian low lean mass. Compared with a worldwide sample (n = 2,003), South Asian skeletons indicate low lean mass. Stature-adjusted lean mass increased significantly over time in South Asia, but to a very minor extent (0.04 z-score units per 1,000 years, adjusted R2 = 0.01). In contrast stature decreased sharply when agriculture was adopted. Our results indicate that low lean mass has characterised South Asians since at least the early Holocene and may represent long-term climatic adaptation or neutral variation. This phenotype is therefore unlikely to change extensively in the short term, so other strategies to address increasing non-communicable disease rates must be pursued.

A cross sectional research on the height, weight and body mass index of children aged 5-6 years in Latvia and its secular changes during the last century.

AIM: To determine the main anthropometric parameters and their changes during the 20th and early 21st centuries for children aged 5-6 and to analyze the nutritional level of the population based on percentage. METHODS: 536 healthy Latvian 5 and 6 year old children were randomly selected and a cross sectional survey was carried out. To collect anthropometric data, the height and weight of each child was measured and BMI calculated. The Kolmogorov-Smirnov Goodness-of-Fit test was used to assess the distribution of data; it was concluded, that the data for both boys and girls in both analyzed age groups fits a normal distribution. Using a t-test statistical tool, the results were compared to our previous study (1998/1999) and to the most significant national anthropometric investigations of the 20th century. RESULTS: During the last decade, the mean values of height and weight (for both boys and girls) have increased in both age groups. The mean BMI value increase for 6 year old boys and girls was not statistically significant (p > 0.05). The BMI mean values for 5 year old boys and girls have decreased (p < 0.05). In both age groups the highest percentage of children are of normal weight. In the past 10 years the proportion of 5 year old underweight children has increased, but the proportion of overweight children has decreased percentage-wise. In all analyzed age groups a little tendency towards increase of the percentage of obese children can be observed. From 1929 to 2007/2009, the overall mean values of height and weight have increased, but BMI mean values have decreased. CONCLUSION: Positive secular changes were observed in body height and weight during the past decade (p < 0.01) and century. The increase in BMI at the beginning of the 21st century in comparison to the end of the 20th century may possibly be facilitated by the increased occurrence of overweight, obesity and related diseases in Latvian children. However, the number of underweight children has increased in the last decade as well.

Frequency of under- and overweight among children and adolescents during the economic transition in Poland.

The aim of this study is to examine the prevalence of underweight, overweight and obesity, using International Obesity Task Force (IOTF) criteria, in four cohorts of children and adolescents living in Poland in different economic eras: communist economy (1977/1978), crisis of the 1980s (1987/1988), political and economic transformation (1992/1994) and the free market economy (2002/2004). Analysis was conducted on a database including 10,934 records for children of the age 7-18 years. In Poland, in the last 26 years of economic and political transformations, the epidemic of obesity was not noticed but the growing incidence of children and adolescents with body mass deficit was observed (p<0.0001) (20.2% of girls in 2002/2004 vs. 11.0% in 1977/1978 and 12.1% of boys in 2002/2004 vs. 7.2% in 1977/1978). Lower parental education and a higher number of children in a family resulted in a higher prevalence of underweight (odds ratio [OR] fluctuated from 1.26 to 1.63). The social effects of the political transformation in Poland significantly affected families with low socio-economic status (SES), and especially more eco-sensitive boys. This result is opposite to the trends observed in Western countries and makes an important contribution to the current knowledge of the course of further changes in weight-to-height ratio at a global scale.